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1

Human telomerase inhibition by substituted acridine derivatives

R. John Harrison, Sharon M. Gowan, Lloyd R. Kelland, Stephen Neidle

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1999

Language:

english

File:

PDF, 348 KB

english, 1999

2

Molecular Modeling Studies on G-Quadruplex Complexes of Telomerase Inhibitors: Structure−Activity Relationships

Read, Martin A., Wood, Alexis A., Harrison, John R., Gowan, Sharon M., Kelland, Lloyd R., Dosanjh, Harvinder S., Neidle, Stephen

Journal:

Journal of Medicinal Chemistry

Year:

1999

Language:

english

File:

PDF, 581 KB

english, 1999

3

Effects of anti-proliferative lichen metabolite, protolichesterinic acid on fatty acid synthase, cell signalling and drug response in breast cancer cells

Bessadóttir, Margrét, Skúladóttir, Edda Á., Gowan, Sharon, Eccles, Suzanne, Ómarsdóttir, Sesselja, Ögmundsdóttir, Helga M.

Journal:

Year:

2014

Language:

english

File:

PDF, 1.49 MB

english, 2014

4

ChemInform Abstract: A Novel Inhibitor of Human Telomerase Derived from 10H-Indolo[3,2-b]quinoline.

Vittorio Caprio, Berengere Guyen, Yaw Opoku-Boahen, John Mann, Sharon M. Gowan, Lloyd M. Kelland, Martin A. Read, Stephen Neidle

Journal:

Year:

2000

File:

PDF, 30 KB

2000

5

Evaluation of by disubstituted acridone derivatives as telomerase inhibitors: the importance of G-quadruplex binding

R. John Harrison, Anthony P. Reszka, Shozeb M. Haider, Barbara Romagnoli, James Morrell, Martin A. Read, Sharon M. Gowan, Christopher M. Incles, Lloyd R. Kelland, Stephen Neidle

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2004

Language:

english

File:

PDF, 293 KB

english, 2004

6

A novel inhibitor of human telomerase derived from 10H-indolo[3,2-b]quinoline

Vittorio Caprio, Berengere Guyen, Yaw Opoku-Boahen, John Mann, Sharon M Gowan, Lloyd M Kelland, Martin A Read, Stephen Neidle

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2000

Language:

english

File:

PDF, 186 KB

english, 2000

7

2,7-Disubstituted Amidofluorenone Derivatives as Inhibitors of Human Telomerase

Perry, Philip J., Read, Martin A., Davies, Rhian T., Gowan, Sharon M., Reszka, Anthony P., Wood, Alexis A., Kelland, Lloyd R., Neidle, Stephen

Journal:

Journal of Medicinal Chemistry

Year:

1999

Language:

english

File:

PDF, 115 KB

english, 1999

8

The Lichens of Fundy National Park, New Brunswick, Canada

Sharon P. Gowan and Irwin M. Brodo

Journal:

Year:

1988

Language:

english

File:

PDF, 12.69 MB

english, 1988

9

The Lichen Genus Porpidia (Porpidiaceae) in North America

Sharon P. Gowan

Journal:

Year:

1989

Language:

english

File:

PDF, 6.65 MB

english, 1989

10

Human Telomerase Inhibition by Regioisomeric Disubstituted Amidoanthracene-9,10-diones

Perry, Philip J., Reszka, Anthony P., Wood, Alexis A., Read, Martin A., Gowan, Sharon M., Dosanjh, Harvinder S., Trent, John O., Jenkins, Terence C., Kelland, Lloyd R., Neidle, Stephen

Journal:

Journal of Medicinal Chemistry

Year:

1998

Language:

english

File:

PDF, 216 KB

english, 1998

11

Molecular cloning of the forkhead transcription factor HNF-3α from a human pulmonary adenocarcinoma cell line

Colin D. Bingle, Sharon Gowan

Journal:

Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression

Year:

1996

Language:

english

File:

PDF, 427 KB

english, 1996

12

Cliostomum (Lichen-Forming Ascomycotina) in North America and Europe

Sharon P. Gowan

Journal:

Year:

1990

Language:

english

File:

PDF, 1.18 MB

english, 1990

13

1,4- and 2,6-Disubstituted Amidoanthracene-9,10-dione Derivatives as Inhibitors of Human Telomerase

Perry, Philip J., Gowan, Sharon M., Reszka, Anthony P., Polucci, Paolo, Jenkins, Terence C., Kelland, Lloyd R., Neidle, Stephen

Journal:

Journal of Medicinal Chemistry

Year:

1998

Language:

english

File:

PDF, 122 KB

english, 1998

14

Advances in establishment and analysis of three-dimensional tumor spheroid-based functional assays for target validation and drug evaluation

Maria Vinci, Sharon Gowan, Frances Boxall, Lisa Patterson, Miriam Zimmermann, William Court, Cara Lomas, Marta Mendiola, David Hardisson, Suzanne A Eccles

Journal:

Year:

2012

Language:

english

File:

PDF, 1.45 MB

english, 2012

15

Antitumor Polycyclic Acridines. 8. 1 Synthesis and Telomerase-Inhibitory Activity of Methylated Pentacyclic Acridinium Salts

Heald, Robert A., Modi, Chetna, Cookson, Jenny C., Hutchinson, Ian, Laughton, Charles A., Gowan, Sharon M., Kelland, Lloyd R., Stevens, Malcolm F. G.

Journal:

Journal of Medicinal Chemistry

Year:

2002

Language:

english

File:

PDF, 217 KB

english, 2002

16

Trisubstituted Acridine Derivatives as Potent and Selective Telomerase Inhibitors

Harrison, R. John, Cuesta, Javier, Chessari, Gianni, Read, Martin A., Basra, Sanji K., Reszka, Anthony P., Morrell, James, Gowan, Sharon M., Incles, Christopher M., Tanious, Farial A., Wilson, W. Davi

Journal:

Journal of Medicinal Chemistry

Year:

2003

Language:

english

File:

PDF, 676 KB

english, 2003

17

A novel serum protein signature associated with resistance to epidermal growth factor receptor tyrosine kinase inhibitors in head and neck squamous cell carcinoma

Box, Carol, Mendiola, Marta, Gowan, Sharon, Box, Gary M., Valenti, Melanie, Brandon, Alexis De Haven, Al-Lazikani, Bissan, Rogers, Susanne J., Wilkins, Anna, Harrington, Kevin J., Eccles, Suzanne A.

Journal:

European Journal of Cancer

Year:

2013

Language:

english

File:

PDF, 525 KB

english, 2013

18

Application of Meso Scale Technology for the Measurement of Phosphoproteins in Human Tumor Xenografts

Gowan, Sharon M., Hardcastle, Anthea, Hallsworth, Albert E., Valenti, Melanie R., Hunter, Lisa-Jane K., de Haven Brandon, Alexis K., Garrett, Michelle D., Raynaud, Florence, Workman, Paul, Aherne, Wyn

Journal:

Assay and Drug Development Technologies

Year:

2007

Language:

english

File:

PDF, 320 KB

english, 2007

19

Decreased Levels of BAG3 in a Family With a Rare Variant and in Idiopathic Dilated Cardiomyopathy

Feldman, Arthur M., Begay, Rene L., Knezevic, Tijana, Myers, Valerie D., Slavov, Dobromir B., Zhu, Weizhong, Gowan, Katherine, Graw, Sharon L., Jones, Kenneth L., Tilley, Douglas G., Coleman, Ryan C.,

Journal:

Journal of Cellular Physiology

Year:

2014

Language:

english

File:

PDF, 1.48 MB

english, 2014

20

A Character Analysis of the Secondary Products of the Porpidiaceae (Lichenized Ascomycotina)

Gowan, Sharon P.

Journal:

Systematic Botany

Year:

1989

Language:

english

File:

PDF, 1.52 MB

english, 1989

21

Flora of New Zealand Lichens.by D. J. Galloway

Review by: Sharon P. Gowan

Journal:

Bulletin of the Torrey Botanical Club

Year:

1986

Language:

english

File:

PDF, 343 KB

english, 1986

22

Untersuchungen an gesteinsbewohnenden xanthonhaltigen Sippen der Flechtengattung Lecidella (Lecanoraceae, Lecanorales) unter besonderer Berücksichtigung von außereuropäischen Proben exklusive Amerikaby J. -G. Knoph

Review by: Sharon P. Gowan

Journal:

Year:

1991

Language:

english

File:

PDF, 269 KB

english, 1991

23

New Depsides from Lichens: Microchemical Methodologies Applied to the Study of new Natural Product Discovered in Herbarium Specimens

Chicita F. Culberson, William Louis Culberson, Sharon Gowan and Anita Johnson

Journal:

American Journal of Botany

Year:

1987

Language:

english

File:

PDF, 2.18 MB

english, 1987

24

CRC Handbook of Lichenologyby M. Galun

Review by: Sharon P. Gowan

Journal:

Year:

1991

Language:

english

File:

PDF, 265 KB

english, 1991

25

Ribosomal DNA Length Polymorphisms within Populations of Xylaria magnoliae (Ascomycotina)

Gowan, Sharon P., Vilgalys, Rytas

Journal:

American Journal of Botany

Year:

1991

Language:

english

File:

PDF, 922 KB

english, 1991

26

Human Thyroid Transcription Factor-1

Gowan, Sharon, Toonen, Rand, Bingle, Colin D.

Journal:

Year:

1997

Language:

english

File:

PDF, 301 KB

english, 1997

27

The lung enriched transcription factor TTF-1 and the ubiquitously expressed proteins Sp1 and Sp3 interact with elements located in the minimal promoter of the rat Clara cell secretory protein gene

TOONEN, Ruud F. G., GOWAN, Sharon, BINGLE, Colin D.

Journal:

Biochemical Journal

Year:

1996

Language:

english

File:

PDF, 426 KB

english, 1996

28

Oct-1 interacts with conserved motifs in the human thyroid transcription factor 1 gene minimal promoter

BINGLE, Colin D, GOWAN, Sharon

Journal:

Biochemical Journal

Year:

1996

Language:

english

File:

PDF, 248 KB

english, 1996

29

Functional status of United States children supported with a left ventricular assist device at heart transplantation

Bulic, Anica, Maeda, Katsuhide, Zhang, Yulin, Chen, Sharon, McElhinney, Doff B., Dykes, John C., Hollander, Amanda M., Hollander, Seth A., Murray, Jenna, Reinhartz, Olaf, Gowan, Mary Alice, Rosenthal,

Journal:

The Journal of Heart and Lung Transplantation

Year:

2017

Language:

english

File:

PDF, 659 KB

english, 2017

30

Immunoassays for the quantification of ALK and phosphorylated ALK support the evaluation of on-target ALK inhibitors in neuroblastoma

Tucker, Elizabeth R., Tall, Jennifer R., Danielson, Laura S., Gowan, Sharon, Jamin, Yann, Robinson, Simon P., Banerji, Udai, Chesler, Louis

Journal:

Molecular Oncology

Year:

2017

Language:

english

File:

PDF, 623 KB

english, 2017

31

Impact of a modified anti-thrombotic guideline on stroke in children supported with a pediatric ventricular assist device

Rosenthal, David N., Lancaster, Chacy A., McElhinney, Doff B., Chen, Sharon, Stein, MaryLyn, Lin, Aileen, Doan, Lan, Murray, Jenna M., Gowan, Mary Alice, Maeda, Katsuhide, Reinhartz, Olaf, Almond, Chr

Journal:

The Journal of Heart and Lung Transplantation

Year:

2017

Language:

english

File:

PDF, 758 KB

english, 2017

32

Outpatient Outcomes of Pediatric Patients with Left Ventricular Assist Devices

Chen, Sharon, Lin, Aileen, Liu, Esther, Gowan, Maryalice, May, Lindsay J., Doan, Lan N., Almond, Christopher S., Maeda, Katsuhide, Reinhartz, Olaf, Hollander, Seth A., Rosenthal, David N.

Journal:

Year:

2015

Language:

english

File:

PDF, 224 KB

english, 2015

33

Filamin C Truncation Mutations Are Associated With Arrhythmogenic Dilated Cardiomyopathy and Changes in the Cell–Cell Adhesion Structures

Begay, Rene L., Graw, Sharon L., Sinagra, Gianfranco, Asimaki, Angeliki, Rowland, Teisha J., Slavov, Dobromir B., Gowan, Katherine, Jones, Kenneth L., Brun, Francesca, Merlo, Marco, Miani, Daniela, Sw

Journal:

JACC: Clinical Electrophysiology

Year:

2018

Language:

english

File:

PDF, 3.54 MB

english, 2018

34

Assessing the mechanism and therapeutic potential of modulators of the human Mediator complex-associated protein kinases

Clarke, Paul A, Ortiz-Ruiz, Maria-Jesus, TePoele, Robert, Adeniji-Popoola, Olajumoke, Box, Gary, Court, Will, Czasch, Stephanie, El Bawab, Samer, Esdar, Christina, Ewan, Ken, Gowan, Sharon, De Haven B

Journal:

Year:

2016

Language:

english

File:

PDF, 5.05 MB

english, 2016

35

Metabolic biomarkers of response to the AKT inhibitor MK-2206 in pre-clinical models of human colorectal and prostate carcinoma

Al-Saffar, Nada M. S., Troy, Helen, Wong Te Fong, Anne-Christine, Paravati, Roberta, Jackson, L. Elizabeth, Gowan, Sharon, Boult, Jessica K. R., Robinson, Simon P., Eccles, Suzanne A., Yap, Timothy A.

Journal:

British Journal of Cancer

Year:

2018

Language:

english

File:

PDF, 1.10 MB

english, 2018

36

NEW DEPSIDES FROM LICHENS: MICROCHEMICAL METHODOLOGIES APPLIED TO THE STUDY OF NEW NATURAL PRODUCTS DISCOVERED IN HERBARIUM SPECIMENS

Culberson, Chicita F., Culberson, William Louis, Gowan, Sharon, Johnson, Anita

Journal:

American Journal of Botany

Year:

1987

File:

PDF, 994 KB

1987

37

RIBOSOMAL DNA LENGTH POLYMORPHISMS WITHIN POPULATIONS OF XYLARIA MAGNOLIAE (ASCOMYCOTINA)

Gowan, Sharon P., Vilgalys, Rytas

Journal:

American Journal of Botany

Year:

1991

Language:

english

File:

PDF, 1.19 MB

english, 1991

38

De novo phosphatidylcholine synthesis is required for autophagosome membrane formation and maintenance during autophagy

Andrejeva, Gabriela, Gowan, Sharon, Lin, Gigin, Wong Te Fong, Anne-Christine LF, Shamsaei, Elham, Parkes, Harry G., Mui, James, Raynaud, Florence I., Asad, Yasmin, Vizcay-Barrena, Gema, Nikitorowicz-B

Journal:

Year:

2019

Language:

english

File:

PDF, 8.07 MB

english, 2019

39

Cliostomum (Lichen-Forming Ascomycotina) in North America and Europe

Gowan, Sharon P.

Journal:

Year:

1990

Language:

english

File:

PDF, 2.74 MB

english, 1990

40

De novo phosphatidylcholine synthesis is required for autophagosome membrane formation and maintenance during autophagy

Andrejeva, Gabriela, Gowan, Sharon, Lin, Gigin, Wong Te Fong, Anne-Christine LF, Shamsaei, Elham, Parkes, Harry G., Mui, James, Raynaud, Florence I., Asad, Yasmin, Vizcay-Barrena, Gema, Nikitorowicz-B

Journal:

Year:

2019

File:

PDF, 8.07 MB

2019

41

Microbiota- and Radiotherapy-Induced Gastrointestinal Side-Effects (MARS) Study: A Large Pilot Study of the Microbiome in Acute and Late-Radiation Enteropathy

Reis Ferreira, Miguel, Andreyev, H. Jervoise N., Mohammed, Kabir, Truelove, Lesley, Gowan, Sharon M., Li, Jia, Gulliford, Sarah L., Marchesi, Julian R., Dearnaley, David P.

Journal:

Clinical Cancer Research

Year:

2019

Language:

english

File:

PDF, 2.52 MB

english, 2019

42

Achieving In Vivo Target Depletion through the Discovery and Optimization of Benzimidazolone BCL6 Degraders

Bellenie, Benjamin R., Cheung, Kwai-Ming J., Varela, Ana, Pierrat, Olivier A., Collie, Gavin W., Box, Gary M., Bright, Michael D., Gowan, Sharon, Hayes, Angela, Rodrigues, Matthew J., Shetty, Kartika

Journal:

Journal of Medicinal Chemistry

Year:

2020

File:

PDF, 9.58 MB

2020

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